✦ LIBER ✦

Radiosynthesis of [11C]-N-methylacyclovir

✍ Scribed by Alan A. Wilson; Peter S. Conti; Robert F. Dannals; Hayden T. Ravert; Henry N. Wagner Jr.

Publisher: John Wiley and Sons
Year: 1991
Tongue: French
Weight: 158 KB
Volume: 29
Category: Article
ISSN: 0022-2135
DOI: 10.1002/jlcr.2580290705

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

A selective and potent analogue of the anti‐herpes agent acyclovir has been labelled with ^11^C in good yield and at high specific activities. 1‐[^11^C]‐Methyl‐9‐(2‐hydroxyethoxy)methyl)guanine may be useful for detecting HSV encephalitis using positron emission tomography.

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