## Abstract Two positron‐emitting analogues of tyrosine, __O__‐[^11^C]methyl‐L‐tyrosine and __O__‐[^18^F]fluoromethyl‐L‐tyrosine were prepared as new tumor imaging agents. The alkylating agent, [^11^C]methyl triflate or [^18^F]fluoromethyl triflate, was simply bubbled through a dimethylsulfoxide so
Radiosynthesis of 1-[18F]fluoroethyl-L-tryptophan as a novel potential amino acid PET tracer
✍ Scribed by Ting Sun; Ganghua Tang; Hua Tian; Xiaoyan Wang; Xianghua Chen; Zhifeng Chen; ShihChen Wang
- Book ID
- 113463848
- Publisher
- Elsevier Science
- Year
- 2012
- Tongue
- English
- Weight
- 443 KB
- Volume
- 70
- Category
- Article
- ISSN
- 0969-8043
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract The involvement of gamma amino butyric acid (GABA) receptors in a variety of neurological and psychiatric diseases has promoted the development and use of radiolabelled benzodiazepines (BZ) for brain imaging by PET. However, these radioligands are unable to distinguish between the vario
## Abstract A fluorine‐18 labeled analog of the widely used chemotherapeutic agent cyclophosphamide was synthesized as a tracer for prognostic imaging with positron emission tomography. 2‐[(2‐Chloro‐2′‐[^18^F]fluoroethyl)amino]‐2H‐1,3,2‐oxazaphosphorinane‐2‐oxide (^18^F‐fluorocyclophosphamide), was
## Abstract The synthesis of a tosylate precursor for the radiosynthesis of a potential PET radiotracer, (S)‐N‐[(1‐ethyl‐2‐pyrrolidinyl)methyl]‐5‐(2‐[^18^F]fluoroethyl)‐2‐ methoxybenzamide is reported. Reaction of ^18^F‐fluoride with the tosylate provides the radiolabeled product in 10–25% yield. S