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RAD51Cgermline mutations found in Spanish site-specific breast cancer and breast-ovarian cancer families

✍ Scribed by Ana Blanco,Sara Gutiérrez-Enríquez…


Book ID
126353424
Publisher
Springer US
Year
2014
Tongue
English
Weight
285 KB
Volume
147
Category
Article
ISSN
0167-6806

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Analysis of RAD51C germline mutations in
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There is strong evidence that overtly inactivating mutations in RAD51C predispose to hereditary breast and ovarian cancer but the prevalence of such mutations, and whether they are associated with a particular clinical phenotype, remains unclear. Resolving these questions has important implications