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RAD51Cgermline mutations in Chinese women with familial breast cancer

✍ Scribed by Zhiyuan Pang; Lu Yao; Juan Zhang; Tao Ouyang; Jinfeng Li; Tianfeng Wang; Zhaoqing Fan; Tie Fan; Benyao Lin; Yuntao Xie

Publisher
Springer US
Year
2011
Tongue
English
Weight
141 KB
Volume
129
Category
Article
ISSN
0167-6806

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✍ Ella R. Thompson; Samantha E. Boyle; Julie Johnson; Georgina L. Ryland; Sarah Sa πŸ“‚ Article πŸ“… 2011 πŸ› John Wiley and Sons 🌐 English βš– 180 KB

There is strong evidence that overtly inactivating mutations in RAD51C predispose to hereditary breast and ovarian cancer but the prevalence of such mutations, and whether they are associated with a particular clinical phenotype, remains unclear. Resolving these questions has important implications