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Pathological features of breast and ovarian cancers inRAD51Cgermline mutation carriers

✍ Scribed by Heidrun Gevensleben,Verena Bossung,Alfons Meindl…


Book ID
126343176
Publisher
Springer
Year
2014
Tongue
English
Weight
107 KB
Volume
465
Category
Article
ISSN
1432-2307

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Analysis of RAD51C germline mutations in
✍ Ella R. Thompson; Samantha E. Boyle; Julie Johnson; Georgina L. Ryland; Sarah Sa 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 180 KB

There is strong evidence that overtly inactivating mutations in RAD51C predispose to hereditary breast and ovarian cancer but the prevalence of such mutations, and whether they are associated with a particular clinical phenotype, remains unclear. Resolving these questions has important implications