✦ LIBER ✦

Pulse sequence for multislice T1ρ-weighted MRI

✍ Scribed by Andrew J. Wheaton; Arijitt Borthakur; Sridhar R. Charagundla; Ravinder Reddy

Publisher: John Wiley and Sons
Year: 2004
Tongue: English
Weight: 234 KB
Volume: 51
Category: Article
ISSN: 0740-3194
DOI: 10.1002/mrm.10705

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✦ Synopsis

Abstract

A 2D multislice spin‐lock (MS‐SL) MR pulse sequence is presented for rapid volumetric T~1ρ~‐weighted imaging. Image quality is compared with T~1ρ~‐weighted data collected using a single‐slice (SS) SL sequence and T~2~‐weighted data from a standard MS spin‐echo (SE) sequence. Saturation of longitudinal magnetization by the application of nonselective SL pulses is experimentally measured and theoretically modeled as T~2ρ~ decay. The saturation data is used to correct the image data as a function of the SL pulse duration to make quantitative measurements of T~1ρ~. Measurements of T~1ρ~ using the saturation‐corrected MS‐SL data are nearly identical to those measured using an SS‐SL sequence. The MS‐SL sequence produces quantitative T~1ρ~ maps of an entire sample volume with the high‐SNR advantages conferred by SE‐based sequences. Magn Reson Med 51:362–369, 2004. © 2004 Wiley‐Liss, Inc.

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