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Comparison of T2*-weighted sequences for functional MRI

✍ Scribed by Xiaoping Hu; Peter Erhard; Tuang Huu Le; Seong-Gi Kim; Ravi Menon; Peter Andersen; Gregor Adriany; John P. Strupp; Kâmil Uǧurbil

Publisher
John Wiley and Sons
Year
1995
Tongue
English
Weight
691 KB
Volume
6
Category
Article
ISSN
0899-9457

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✦ Synopsis

Several sequences, including conventional gradient-echo sequence (e.g., FLASH), gradient-echo echo-planar imaging (EPI), T; prepared ultrafast gradient echo technique (TurboFLASH), and T;-weighted spiral sequence, are currently used for T;-weighted functional magnetic resonance imaging. This paper presents a comparison of FLASH, gradient-echo EPI, and T;-prepared TurboFLASH. Experimental results have demonstrated that these sequences have different susceptibility to physiologic fluctuation, which is likely the dominant source of noise. EPI images exhibit the lowest relative fluctuation, while images obtained by FLASH and TurboFLASH, respectively, display similar relative fluctuation. Functional maps generated using these sequences are comparable but exhibit different sensitivity to activation from large vessels. Consequently, interpretation of activation results from various maps should take into account the difference in the sequences. 0 1995 John Wiley 8 Sons, inc.

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