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Protection Effects of Taurine Supplementation against Cisplatin-Induced Nephrotoxicity in Rats

✍ Scribed by Saad, Sherif Y.; Al-Rikabi, Ammar C.


Book ID
120654150
Publisher
S. Karger AG
Year
2002
Tongue
English
Weight
320 KB
Volume
48
Category
Article
ISSN
0009-3157

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Key words: nephrotoxicity; cisplatin; radical scavengers; methimazole; rat In adult rats 6 mg kg -1 body wt. cisplatin given i.p. was nephrotoxic. Four days of i.p. treatment with 40 mg kg -1 body wt. methimazole, which started 1 day before CP, prevented increases in blood urea nitrogen and in the r