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Protective effect ofl-carnitine versus amifostine against cisplatin-induced nephrotoxicity in rats

✍ Scribed by Sernaz Uzunoglu; Hakan Karagol; Fulya Ozpuyan; Rusen Cosar; Irfan Cicin; Vuslat Yurutcaloglu; Bengü Denizli; Özgür Tanriverdi; Necdet Sut; Zafer Kocak

Book ID
107577359
Publisher
Springer US
Year
2010
Tongue
English
Weight
646 KB
Volume
28
Category
Article
ISSN
1357-0560

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Protective Effects of Methimazole against Cisplatin-induced Nephrotoxicity in Rats
✍ Helmut Bräunlich; Dorothea Appenroth; Christian Fleck 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 159 KB 👁 2 views

Key words: nephrotoxicity; cisplatin; radical scavengers; methimazole; rat In adult rats 6 mg kg -1 body wt. cisplatin given i.p. was nephrotoxic. Four days of i.p. treatment with 40 mg kg -1 body wt. methimazole, which started 1 day before CP, prevented increases in blood urea nitrogen and in the r