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Protective Effect of Hidrosmin Against Cisplatin-induced Acute Nephrotoxicity in Rats

✍ Scribed by R. CORCOSTEGUI; L. LABEAGA; J. K. ARTECHE; A. ORJALES

Book ID
118110838
Publisher
Pharmaceutical Press
Year
1998
Tongue
English
Weight
251 KB
Volume
4
Category
Article
ISSN
2042-7158

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Key words: nephrotoxicity; cisplatin; radical scavengers; methimazole; rat In adult rats 6 mg kg -1 body wt. cisplatin given i.p. was nephrotoxic. Four days of i.p. treatment with 40 mg kg -1 body wt. methimazole, which started 1 day before CP, prevented increases in blood urea nitrogen and in the r