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Promoter analysis of the human mismatch repair gene hMSH2

โœ Scribed by Yuki Iwahashi; Emi Ito; Yuka Yanagisawa; Yoshimitsu Akiyama; Yasuhito Yuasa; Takashi Onodera; Kazuo Maruyama

Book ID
117523097
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
261 KB
Volume
213
Category
Article
ISSN
0378-1119

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## Background: The human mismatch repair (mmr) gene hmsh2 (human muts homolog-2) is a dna repair gene that has been reported to be mutated in 40% of hereditary nonpolyposis colon cancer (hnpcc) kindreds and a small percentage of sporadic tumors. hnpcc is a cancer predisposition syndrome with an inc