𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Cell type specificity in alternative splicing of the human mismatch repair gene hMSH2

✍ Scribed by Clarke, Luka A; Jordan, Peter; Boavida, Maria Guida


Book ID
110024966
Publisher
Nature Publishing Group
Year
2000
Tongue
English
Weight
215 KB
Volume
8
Category
Article
ISSN
1018-4813

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Mutation of the mismatch repair gene hMS
✍ Lauretta Levati; Giancarlo Marra; Teresa Lettieri; Stefania D'Atri; Patrizia Ver πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 186 KB πŸ‘ 2 views

Cell killing by monofunctional methylating agents is due mainly to the formation of adducts at the O 6 position of guanine. These methyl adducts are removed from DNA by the O 6 -alkylguanine DNA alkyltransferase (OGAT). The mechanism by which O 6 -methylguanine (O 6 meG) induces cell death in OGAT-d

Expression of the human mismatch repair
✍ Fredrick S. Leach; Jer-Tsong Hsieh; Kyle Molberg; M. Hossein Saboorian; John D. πŸ“‚ Article πŸ“… 2000 πŸ› John Wiley and Sons 🌐 English βš– 224 KB πŸ‘ 2 views

## Background: The human mismatch repair (mmr) gene hmsh2 (human muts homolog-2) is a dna repair gene that has been reported to be mutated in 40% of hereditary nonpolyposis colon cancer (hnpcc) kindreds and a small percentage of sporadic tumors. hnpcc is a cancer predisposition syndrome with an inc

Human mismatch repair gene (hMSH2) produ
✍ Tie-Xiong Jin; Mutsuo Furihata; Ichiro Yamasaki; Masayuki Kamada; Sheng-Ben Lian πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 288 KB πŸ‘ 2 views

## Background: Several convincing studies have shown that the hmsh2 gene plays major roles in mismatch repair by recognizing mismatched bases and preventing mutations during dna replication. loss of this function may result in the accumulation of dna replication errors or even the mutator phenotype