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Prognostic implications of hypoxia-inducible factor-1α in epidermal growth factor receptor-negative non-small cell lung cancer

✍ Scribed by Park, Sanghui; Ha, Seung Yeon; Cho, Hyun Yee; Chung, Dong Hae; Kim, Na Rae; Hong, Junshik; Cho, Eun Kyung


Book ID
119320444
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
729 KB
Volume
72
Category
Article
ISSN
0169-5002

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✍ Daniel E.B. Swinson; J. Louise Jones; Giles Cox; Donna Richardson; Adrian L. Har 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 French ⚖ 199 KB

## Abstract Hypoxia‐inducible factor (HIF)‐1α is the regulatory subunit of HIF‐1 that is stabilized under hypoxic conditions. Under different circumstances, HIF‐1α may promote both tumorigenesis and apoptosis. There is conflicting data on the importance of HIF‐1α as a prognostic factor. This study