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Expression of Hypoxia Inducible Factor 1α and Its Significance in Non-small Cell Lung Cancer

✍ Scribed by Shu XIA; Shiying YU; Xianglin YUAN

Publisher
Springer
Year
2005
Tongue
English
Weight
135 KB
Volume
4
Category
Article
ISSN
1610-1979

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✍ Daniel E.B. Swinson; J. Louise Jones; Giles Cox; Donna Richardson; Adrian L. Har 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 French ⚖ 199 KB

## Abstract Hypoxia‐inducible factor (HIF)‐1α is the regulatory subunit of HIF‐1 that is stabilized under hypoxic conditions. Under different circumstances, HIF‐1α may promote both tumorigenesis and apoptosis. There is conflicting data on the importance of HIF‐1α as a prognostic factor. This study