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Prevalence of mutations in APC, CTNNB1, and BRAF in Tunisian patients with sporadic colorectal cancer

✍ Scribed by Karim Bougatef; Slah Ouerhani; Amel Moussa; Nadia Kourda; Florence Coulet; Chrystelle Colas; Yannick Blondeau Lahely; Tawfik Najjar; Sarra Ben Jilani; Amel Benammar-Elgaaied; Florent Soubrier; Raja Marrakchi

Book ID
113513402
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
215 KB
Volume
187
Category
Article
ISSN
0165-4608

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Somatic mutation of MutYH in Tunisian pa
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✍ Karim Bougatef; Raja Marrakchi; Nadia Kourda; Yannick Blondeau Lahely; Sarra Bal πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 181 KB πŸ‘ 1 views

## Abstract The __MutYH__ gene is an adenine‐specific DNA glycosylase that prevents G/T transversions. Germline mutation in this gene causes __MYH__‐associated polyposis (MAP) that predispose to hereditary colorectal cancer (CRC). This study describes for the first time the association of the __Mut