✦ LIBER ✦

Prevalence and Phenotypes of APC and MUTYH Mutations in Patients With Multiple Colorectal Adenomas

✍ Scribed by Grover, Shilpa; Kastrinos, Fay; Steyerberg, Ewout W.; Cook, E. Francis; Dewanwala, Akriti; Burbidge, Lynn Anne; Wenstrup, Richard J.; Syngal, Sapna

Book ID: 118142952
Publisher: American Medical Association
Year: 2012
Tongue: English
Weight: 180 KB
Volume: 308
Category: Article
ISSN: 0098-7484
DOI: 10.1001/jama.2012.8780

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Germline MUTYH (MYH) mutations in Portug

Germline MUTYH (MYH) mutations in Portuguese individuals with multiple colorectal adenomas

✍ Glória Isidro; Francisco Laranjeira; Ana Pires; Júlio Leite; Fernando Regateiro; 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 73 KB

Germinal mutations in the base excision repair (BER) gene MUTYH (MYH) have recently been described in association with predisposition to multiple colorectal adenomas and cancer. In contrast to the classic dominant condition of familial adenomatous polyposis (FAP) due to germinal mutations in the APC

APC or MUTYH mutations account for the m

APC or MUTYH mutations account for the majority of clinically well-characterized families with FAP and AFAP phenotype and patients with more than 30 adenomas

✍ B Filipe; C Baltazar; C Albuquerque; S Fragoso; P Lage; I Vitoriano; S Mão de Fe 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 508 KB

Germline mutations of theMYHgene in Kore

Germline mutations of theMYHgene in Korean patients with multiple colorectal adenomas

✍ Duck-Woo Kim; Il-Jin Kim; Hio-Chung Kang; Sang-Geun Jang; Kun Kim; Hyun-Ju Yoon; 📂 Article 📅 2007 🏛 Springer 🌐 English ⚖ 190 KB

Prevalence of mutations in APC, CTNNB1,

Prevalence of mutations in APC, CTNNB1, and BRAF in Tunisian patients with sporadic colorectal cancer

✍ Karim Bougatef; Slah Ouerhani; Amel Moussa; Nadia Kourda; Florence Coulet; Chrys 📂 Article 📅 2008 🏛 Elsevier Science 🌐 English ⚖ 215 KB

Novel germline APC variants in patients

Novel germline APC variants in patients with multiple adenomas

✍ Simona Pedemonte; Stefania Sciallero; Viviana Gismondi; Paola Stagnaro; Roberta 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 202 KB 👁 1 views

Chain-terminating germline APC mutations are responsible for adenomatous polyposis coli (APC). In the present work, we tested the hypothesis that germline APC mutations may be present in some patients with a milder phenotype, i.e., multiple synchronous colorectal adenomas. Eighteen patients with 3 o

MUTYH-associated polyposis – variability

MUTYH-associated polyposis – variability of the clinical phenotype in patients with biallelic and monoallelic MUTYH mutations and report on novel mutations

✍ M Morak; A Laner; U Bacher; C Keiling; E Holinski-Feder 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 647 KB