Mutations of BRAF are associated with ex
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Koji Koinuma; Kazuhisa Shitoh; Yasuyuki Miyakura; Taiji Furukawa; Yoshihiro Yama
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Article
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2003
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John Wiley and Sons
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French
โ 175 KB
๐ 2 views
## Abstract Activating mutations of __BRAF__ have been frequently observed in microsatellite unstable (MSI^+^) colorectal carcinomas (CRCs), in which mutations of __BRAF__ and __KRAS__ are mutually exclusive. Previously, we reported that hypermethylation of __hMLH1__ might play an important role in