## Abstract The CpG island methylator phenotype (CIMP) with widespread promoter CpG island methylation is a phenotype in colorectal cancer, associated with microsatellite instability (MSI) and __BRAF__ mutation. Genomeβwide hypomethylation may also play an important role in genomic instability. How
CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer
β Scribed by Weisenberger, Daniel J; Siegmund, Kimberly D; Campan, Mihaela; Young, Joanne; Long, Tiffany I; Faasse, Mark A; Kang, Gyeong Hoon; Widschwendter, Martin; Weener, Deborah; Buchanan, Daniel
- Book ID
- 109919395
- Publisher
- Nature Publishing Group
- Year
- 2006
- Tongue
- English
- Weight
- 581 KB
- Volume
- 38
- Category
- Article
- ISSN
- 1061-4036
- DOI
- 10.1038/ng1834
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