✦ LIBER ✦

Cyclin D1 is frequently overexpressed in microsatellite unstable colorectal cancer, independent of CpG island methylator phenotype

✍ Scribed by K Nosho; T Kawasaki; A T Chan; M Ohnishi; Y Suemoto; G J Kirkner; C S Fuchs; S Ogino

Book ID: 108780630
Publisher: John Wiley and Sons
Year: 2008
Tongue: English
Weight: 590 KB
Volume: 53
Category: Article
ISSN: 0309-0167
DOI: 10.1111/j.1365-2559.2008.03161.x

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

LINE-1 hypomethylation is inversely asso

LINE-1 hypomethylation is inversely associated with microsatellite instability and CpG island methylator phenotype in colorectal cancer

✍ Shuji Ogino; Takako Kawasaki; Katsuhiko Nosho; Mutsuko Ohnishi; Yuko Suemoto; Gr 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 French ⚖ 210 KB

## Abstract The CpG island methylator phenotype (CIMP) with widespread promoter CpG island methylation is a phenotype in colorectal cancer, associated with microsatellite instability (MSI) and __BRAF__ mutation. Genome‐wide hypomethylation may also play an important role in genomic instability. How

SIRT1 histone deacetylase expression is

SIRT1 histone deacetylase expression is associated with microsatellite instability and CpG island methylator phenotype in colorectal cancer

✍ Nosho, Katsuhiko; Shima, Kaori; Irahara, Natsumi; Kure, Shoko; Firestein, Ron; B 📂 Article 📅 2009 🏛 Nature Publishing Group 🌐 English ⚖ 276 KB

Left-Sided microsatellite unstable color

Left-Sided microsatellite unstable colorectal cancers show less frequent methylation of hMLH1 and CpG island methylator phenotype than right-sided ones

✍ Junichiro Tanaka; Toshiaki Watanabe; Takamitsu Kanazawa; Tomohiro Tada; Yoshihir 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 143 KB

CpG island methylator phenotype underlie

CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer

✍ Weisenberger, Daniel J; Siegmund, Kimberly D; Campan, Mihaela; Young, Joanne; Lo 📂 Article 📅 2006 🏛 Nature Publishing Group 🌐 English ⚖ 581 KB

BRAF mutation, CpG island methylator phe

BRAF mutation, CpG island methylator phenotype and microsatellite instability occur more frequently and concordantly in mucinous than non-mucinous colorectal cancer

✍ Hirofumi Tanaka; Guoren Deng; Koji Matsuzaki; Sanjay Kakar; Grace E. Kim; Soichi 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 French ⚖ 95 KB

## Abstract Mucinous colorectal cancer (CRC) has been reported to have distinct clinicopathological and genetic characteristics. However, the incidence and the relationship among microsatellite instability (MSI), CpG island methylator phenotype (CIMP) and __BRAF__ and __KRAS__ mutations in mucinous

APC gene methylation is inversely correl

APC gene methylation is inversely correlated with features of the CpG island methylator phenotype in colorectal cancer

✍ Barry Iacopetta; Fabienne Grieu; Wei Li; Andrew Ruszkiewicz; Maria Caruso; James 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 French ⚖ 271 KB

## Abstract The notion of a CpG island methylator phenotype (CIMP) was proposed to describe a subset of colorectal cancers (CRC) displaying frequent and concordant methylation of CpG islands located within gene promoter regions. Some workers have failed to observe associations between CIMP and spec