## Abstract The CpG island methylator phenotype (CIMP) with widespread promoter CpG island methylation is a phenotype in colorectal cancer, associated with microsatellite instability (MSI) and __BRAF__ mutation. Genomeβwide hypomethylation may also play an important role in genomic instability. How
High CpG island methylator phenotype is associated with lymph node metastasis and prognosis in gastric cancer
β Scribed by Hua-Yun Chen; Bao-He Zhu; Chang-Hua Zhang; Dong-Jie Yang; Jian-Jun Peng; Jian-Hui Chen; Fa-Keng Liu; Yu-Long He
- Book ID
- 108589200
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 305 KB
- Volume
- 103
- Category
- Article
- ISSN
- 1347-9032
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## Abstract The notion of a CpG island methylator phenotype (CIMP) was proposed to describe a subset of colorectal cancers (CRC) displaying frequent and concordant methylation of CpG islands located within gene promoter regions. Some workers have failed to observe associations between CIMP and spec
DNA ploidy microspectrophotometrically determined in 254 patients with gastric carcinoma was investigated from the standpoint of tumor invasion, lymph node metastasis, and prognosis. DNA distribution patterns were grouped into low and high ploidies. The 24.0% frequency in the high ploidy group, at t