## Abstract A method for preparing tritiumโlabelled ryanodine is described. The alkaloid was first brominated, and the bromoryanodines were separated from the reaction mixture by thin layer chromatography; NMR analysis at this stage showed substitution of pyrrole protons by bromine. Bromoryanodine
Preparation of tritium labelled L-phenylalanine
โ Scribed by Ch. Gerday; W. G. Verly
- Publisher
- John Wiley and Sons
- Year
- 1968
- Tongue
- French
- Weight
- 204 KB
- Volume
- 4
- Category
- Article
- ISSN
- 0022-2135
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โฆ Synopsis
Tritiated N-chloracetyl-DL-phenylalanine, obtained by reduction of the N-chloracetyl-dehydrophenylalanine with tritiated hydrogen, is hydrolysed by carboxypeptidase A . The method gives L-phenyl-al~nine-2,3-~H of high optical purity and with any specific activity up to 60 curies per millimole.
๐ SIMILAR VOLUMES
## Abstract Tritiated dextran and inulin were prepared by both a catalytic solid state and a liquid phase isotope exchange with gaseous tritium. The liquid phase procedure is convenient for preparation of the polysaccharides with specific activities up to 5 mCi/g, while the solid state procedure al
On hydrogenation of the 2,6-bis(phenylhydrazone) of 2,6-diketopimelic acid with carrierfree tritium a very low specijic activity was achieved, due to the labile C-T-bonds in the a-positions. 2,6-Di~minopimelic-4-~H acid of spec. activity 790 mCilmmole was obtained by catalytic dehydrohalogenation of
## Abstract The preparation of tritiated phosphoryl choline containing linear polymers by the reduction of an acetylenically unsaturated polymer with tritium gas is described. Homogeneous catalysis was used and the product was analysed by ^1^H and ^3^Hโnmr spectroscopy. The use of lanthanide shift
## Abstract ฮฑโDihydrograyanotoxin II has been labelled with tritium at the Cโ10 and Cโ19 positions by catalytic hydrogenation of grayanotoxin II. Pdโcatalyzed reduction in tetrahydrofuran produced the ฮฑโform exclusively. The compound was obtained with specific activity 1.21 Ci/mmole and with 99% ra
## Abstract The position of the tritium label in DLโ[Gโ3H] phenylalanine prepared by platinum catalysed exchange in tritiated water at elevated temperatures has been determined by chemical degradation and by tritium nuclear magnetic resonance speotroscopy. There is good agreement between the result