## Abstract Conditions are described for the treatment of proline with hydrogen peroxide, ascorbic acid, and ferrous ions to produce 3‐hydroxyproline in 5–6% yield. Several reaction products are formed, but they can be separated chromatographically to yield pure trans‐3‐hydroxyproline. Synthesis of
Preparation of [Thienyl-3-14C]temocillin
✍ Scribed by R. Freer; B. B. Hatt; M. M. Mitchell; D. D. Morecombe
- Publisher
- John Wiley and Sons
- Year
- 1987
- Tongue
- French
- Weight
- 436 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0022-2135
No coin nor oath required. For personal study only.
✦ Synopsis
thienyl-3-14C]Temocillin has been prepared from [ l-14C]chloroacetic acid via 3-[ 3-I4C] thienylmalonic acid.
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## Abstract A novel five‐step synthesis of 3,3′‐ dichlorobenzidine‐(phenyl‐U^14^C) dihydrochloride is described. The method consists of the preparation of benzidine‐(phenyl‐U‐^14^C) followed by acetylation, chlorination with N‐chlorosuccinimide (NCS), and hydrolysis. The specific activity of the pr
## Abstract Methyl cinnamate ‐3‐^14^C is reduced smoothly in excellent yield to cinnamyl alcohol ‐3‐^14^C by aluminum hydride. without attack of the double bond. After purification by column chromatography cinnamyl alcohol ‐3‐^14^C is obtained with a radioactive overall yield of 65% based on cinnam
## Abstract La carbonatation avec ^14^CO~2~ du Mméthylthiométhyllithium a fourni l'acide méthylthio‐2 acétique(^14^C‐1) avec un rendement de 83%, dont la réduction par LiA1H~4~ a conduit au méthylthio‐2 éthanol‐1 (^14^C‐1) qui a été transformé en chlorure correspondant par action de la tri‐n‐octylp