Since its introduction to medicine several years ago, diphenylhydantoin (DPH) has been widely used in the treatment of epilespy, both in adults and children.( 2) The effects of the drug is well correlated with the plasma levels. high levels have adverse effects. ( 3 )
Preparation of high specific activity tin-125 radiotracer
β Scribed by John W. Winchester
- Publisher
- Elsevier Science
- Year
- 1961
- Tongue
- English
- Weight
- 109 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0003-2670
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π SIMILAR VOLUMES
The preparation of the 61-specific ligand 7-benzylidenenaltrexone (BNTX), labeled with tritium at high specific activity (14.4 Ciimmol) was prepared in 33% yield and >98% purity by the aldol condensation of high specific activity [15,1 6-3H]naltrexone with benzaldehyde at high dilution.
Isotopic exchange of hydrogen in a system of s~lvent-water-~H was used to prepare 5-Juoroorotic a ~i d -~H ( G ) which was decarboxylated and the hydrogen-3H removed from labile bonds to yield 5'-Juorouracil-6-3H. It was found in tracer experiments that a suitable solvent for the isotopic exchange o
High-specific-activity D-[3-3H]pantothenic acid (5 Ci/mmol) was prepared from commercially available beta-[3-3H]alanine employing Escherichia coli strain DV1 (panD2 pan F1). This strain is defective in beta-alanine synthesis and pantothenate uptake, and under appropriate growth conditions converted