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Preparation of 2-iodomorphine for use in radioimmunoassay

โœ Scribed by P A Mason; B Law; R E Ardrey

Publisher
John Wiley and Sons
Year
1981
Tongue
French
Weight
291 KB
Volume
18
Category
Article
ISSN
0022-2135

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โœฆ Synopsis

Abstract

A method is described for the preparation of ^125^iodomorphine. The structure of this compound was confirmed by synthesis of ^127^iodomorphine and subsequent mass spectral studies. ^125^Iodomorphine has proved to be chemically very stable and has been shown to be bound avidly by a morphine antiserum. It should, therefore, prove to be very useful for the development of a morphine radioimmunoassay.

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