Prediction of sedimentation coefficients of random coil polymers
β Scribed by C. M. Kok; Alfred Rudin
- Publisher
- John Wiley and Sons
- Year
- 1982
- Tongue
- English
- Weight
- 415 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0021-8995
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The sedimentation coefficients of branched and cyclic replicating DNA structures have been calculated taking into account both chain stiffness and excluded volume effects. For branched DNA, the calculated ratio So(a)/SO(0) of the sedimentation coefficient at degree of replication a to that a t a = 0
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## Abstract The ability to predict diffusion coefficients is important in the design, analysis, and operation of plasmid downstream processing operations such as membrane and fixedβbed chromatography. A correlation is proposed to predict the diffusion coefficient, __D__, of supercoiled plasmid DNA