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Photodecomposition of CI-981, an HMG-CoA reductase inhibitor

✍ Scribed by Timothy R. Hurley; Charles E. Colson; Scott A. Clipper; Susan E. Uhlendorf; Michael D. Reily

Publisher: Elsevier Science
Year: 1993
Tongue: French
Weight: 358 KB
Volume: 49
Category: Article
ISSN: 0040-4020
DOI: 10.1016/s0040-4020(01)86297-9

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✦ Synopsis

Abstmet: Upon exposure to intense simulated sunlight, CI-981 (1) readily decomposes into three major by-products. This paper reports on the products formed when I is decomposed in acetommlelwater solutions under intense simulated sunlight, ult~~~olet b&t filtered at 254 mn and visible light, In&ded is a dim&on of the isOkZhOn of the major by-products and passable mechamsms for the photooxi&ive processes which lead to them.

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