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Enantioselective synthesis of a new fluoro-substituted HMG-COA reductase inhibitor

✍ Scribed by E. Baader; W. Bartmann; G. Beck; P. Below; A. Bergmann; H. Jendralla; K. Keßeler; G. Wess

Publisher
Elsevier Science
Year
1989
Tongue
French
Weight
235 KB
Volume
30
Category
Article
ISSN
0040-4039

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✦ Synopsis

The synthesis of a new fluoro-substituted 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor 2 in high optical purity via addition of the chiral enolate 12 to fluoro aldehyde 82 is described.

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