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A New and Efficient Synthesis of the HMG-CoA Reductase Inhibitor Pitavastatin

✍ Scribed by Murat Acemoglu; Andre Brodbeck; Angel Garcia; Dominique Grimler; Marc Hassel; Bernhard Riss; Robert Schreiber

Publisher: John Wiley and Sons
Year: 2007
Tongue: German
Weight: 23 KB
Volume: 90
Category: Article
ISSN: 0018-019X
DOI: 10.1002/hlca.200790146

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✦ Synopsis

On p. 1074, in Scheme 3, the correct formula of NK-104 should be as follows:

On p. 1077, line 16 should read as follows:

(390 ml) was cooled to À 788, and 1.6m BuLi in hexane (374.4 g, 881 mmol) was added under 3) On p. 1078, line 15 should read as follows:

As HPLC revealed the presence of more than 10% of 8 in the mixture, 5 (21.17 g, 44.9 mmol) and K 2 CO 3

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