Synthesis of vinyl pyrophosphonate analo
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Ibrahim Zgani; Chantal Menut; Jean Louis MontΓ©ro
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Article
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2002
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John Wiley and Sons
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English
β 127 KB
## Abstract The synthesis of new bioisosteric analogues of farnesyl pyrophosphate where a vinyl pyrophosphonate replaced the pyrophosphate moiety is described. These compounds have been prepared using a HornerβWadsworthβEmmons procedure and a modified Michelson reaction. They have been evaluated fo