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Inhibition of human smooth muscle cell proliferation in culture by farnesyl pyrophosphate analogues, inhibitors of in vitro protein:farnesyl transferase

✍ Scribed by Louis H. Cohen; Elsbet Pieterman; Rick E.W. van Leeuwen; Junrong Du; Pascale Negre-Aminou; A.Rob P.M. Valentijn; Mark Overhand; Gijs A. van der Marel; Jacques H. van Boom

Book ID: 113994292
Publisher: Elsevier Science
Year: 1999
Tongue: English
Weight: 550 KB
Volume: 57
Category: Article
ISSN: 0006-2952
DOI: 10.1016/s0006-2952(98)00322-0

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## Abstract Replacement of L‐valine with D‐valine in a standard culture medium can selectively inhibit fibroblast proliferation. The aim of the present study was to investigate whether human myometrial cells cultured with D‐valine instead of L‐valine can survive and express their characteristics. C