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Photo-oxidation in the synthesis of17O and 18O labelled compounds: Synthesis of xanthone-18O1

✍ Scribed by Henry J. Pownall

Publisher
John Wiley and Sons
Year
1974
Tongue
French
Weight
135 KB
Volume
10
Category
Article
ISSN
0022-2135

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✦ Synopsis

Abstract

It it shown that the photo‐oxidation of aromatic molecules containing an active methylene group can be used to introduce isotopic oxygen. Photo‐oxidation of xanthene results in the formation of xanthone with the oxygen label appearing in the product at the carbonyl group. In this way, 100% enrichment can be realized. A brief discussion of other systems to which this method may be extended is also given.

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