## Abstract A method is described by which ^18^O‐DMF can be prepared conveniently and in very high yields (∼ 90%) by reacting at room temperature an equimolar quantity of benzoyl chloride, DMF and ^18^O‐labelled water.
A short and convenient synthesis of [1-18O] and [4-18O] vitamin K1
✍ Scribed by Claude Boullais; Jacques Delvallee
- Publisher
- John Wiley and Sons
- Year
- 1998
- Tongue
- French
- Weight
- 227 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0022-2135
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract It it shown that the photo‐oxidation of aromatic molecules containing an active methylene group can be used to introduce isotopic oxygen. Photo‐oxidation of xanthene results in the formation of xanthone with the oxygen label appearing in the product at the carbonyl group. In this way, 1
The s y n t h e s i s of c r y s t a l l i n e potassium phosphate-180b (monobasic) of high (% 90%) i s o t o p i c p u r i t y s t a r t i n g with PC15 and 99% water-"O is described. tamination by metaphosphates and pyrophosphate is 85%.
## Abstract 8‐[^18^O]Hydroxy‐2′‐deoxyguanosine was synthesized starting from 8‐bromo‐2′‐deoxyguanosine and the sodium salt of [^18^O]benzyl alcohol, resulting in the intermediate 8‐[^18^O]benzyloxy‐2′‐deoxyguanosine. Subsequent reduction by catalytic transfer hydrogenation, yielded the desired prod