A convenient preparation of 18O-dimethylformamide
✍ Scribed by R. Rao Koganty; George A. Digenis
- Publisher
- John Wiley and Sons
- Year
- 1974
- Tongue
- French
- Weight
- 121 KB
- Volume
- 10
- Category
- Article
- ISSN
- 0022-2135
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✦ Synopsis
Abstract
A method is described by which ^18^O‐DMF can be prepared conveniently and in very high yields (∼ 90%) by reacting at room temperature an equimolar quantity of benzoyl chloride, DMF and ^18^O‐labelled water.
📜 SIMILAR VOLUMES
180]-Chlorocarbonylsulfenyl chloride with an isotopic purity of 92% was prepared in three steps starting with the [180]-hydrolysis of 2-ethyl-l,3-dioxolane to [' 80]-propanal, which was then converted to [180]-g-1 -methylpropyl ?-methyl dithiocarbonate, which was then chlorinated to give the title c
## Abstract A method of preparing ^18^O‐labelled nicotinamide, involving cyanopyridine, H~2~ ^18^O, and 1,1′3,3′‐tetramethylguanidine as a catalyst is described. The desired product is produced in 91% chemical yield and 97.5% isotopic incorporation. Copyright © 2002 John Wiley & Sons, Ltd.
## Abstract Sodium acetate‐^18^O~2~ is synthesized by the hydrolysis of triethyl orthoacetate with water‐^18^O in 89% chemical yield with a 1.1 to 1.2‐fold dilution of the isotopic label contained in water‐^18^O.
mixture with heptane, from which it is crystallized a t -80 "C. The yield was 27 % calculated on the total amount of starting material, and 54 "/, on the amount consumed. CzH5Cp2ZrCI is a crystalline, intensely yellow, diamagnetic compound [xg = -(0.44 & 0.04) x 10-6 E.M.U./g], which is decomposed