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Phosphodiesterases (PDEs) and PDE inhibitors for treatment of LUTS

โœ Scribed by Karl-Erik Andersson; Stefan Uckert; Christian Stief; Petter Hedlund


Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
256 KB
Volume
26
Category
Article
ISSN
0733-2467

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Phosphodiesterase 5 (PDE 5) inhibitors f
โœ Dmitri Pissarnitski ๐Ÿ“‚ Article ๐Ÿ“… 2006 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 419 KB

## Abstract The role of phosphodiesterase type 5 (PDE5) in the mechanism of male erection has been well understood, and several drugs inhibiting this enzyme are being used for the treatment of erectile dysfunction (ED). Discovery of inhibitors with improved selectivity versus other PDE isozymes cou