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Phosphodiesterase 5 (PDE5) Inhibitors for the Treatment of Male Erectile Disorder: Attaining Selectivity versus PDE6

โœ Scribed by Dmitri Pissarnitski


Publisher
John Wiley and Sons
Year
2006
Weight
8 KB
Volume
37
Category
Article
ISSN
0931-7597

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Phosphodiesterase 5 (PDE 5) inhibitors f
โœ Dmitri Pissarnitski ๐Ÿ“‚ Article ๐Ÿ“… 2006 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 419 KB

## Abstract The role of phosphodiesterase type 5 (PDE5) in the mechanism of male erection has been well understood, and several drugs inhibiting this enzyme are being used for the treatment of erectile dysfunction (ED). Discovery of inhibitors with improved selectivity versus other PDE isozymes cou