Phosphodiesterase 5 (PDE 5) inhibitors f
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Dmitri Pissarnitski
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Article
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2006
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John Wiley and Sons
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English
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## Abstract The role of phosphodiesterase type 5 (PDE5) in the mechanism of male erection has been well understood, and several drugs inhibiting this enzyme are being used for the treatment of erectile dysfunction (ED). Discovery of inhibitors with improved selectivity versus other PDE isozymes cou