Phehylthio group as a protecting group of phosphates in oligonucleotide synthesis via phosphotriester approach
โ Scribed by Mitsuo Sekine; Tsujiaki Hata
- Publisher
- Elsevier Science
- Year
- 1975
- Tongue
- French
- Weight
- 223 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
4-Cyano-2-butenyl (CB) is a new type of protecting group for the intemucleotidic bonds in the synthesis of oligodeoxyribonucleotides by the phosphoramidite approach. This group is stable to acidic conditions and can be removed under mild conditions by a 8-elimination pathway using aqueous ammonium h
2-Methylsulfonylethoxy dichlorophosphine has been converted into the mono-N-morpholino derivative and applied for the preparation of 5'-D,N-protected d-nucleoside-3'-phosphoramidites. The latter intermediates could be used in the presence of 1-hydroxyben~otriazole for the formation of 3'-5'-phosphot
Absbwct: 2-Diphenylmethylsilylethyl (DPSE) is a new protecting group for internucleotidic bonds in the synthesis of oligodeoqribo nucleotides by the phosphoramidite approach. This group is stable to acidic conditions and can be removed under mild /3$ragmentation conditions using aqueous ammonium hyd