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Phase angle is a prognostic factor for survival in amyotrophic lateral sclerosis

✍ Scribed by Desport, Jean-Claude; Marin, Benoit; Funalot, Benoït; Preux, Pierre-Marie; Couratier, Philippe

Book ID
120028604
Publisher
Informa plc
Year
2008
Tongue
English
Weight
101 KB
Volume
9
Category
Article
ISSN
1471-180X

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## Abstract ## Objective To elucidate the role of cyclooxygenase‐1 (Cox1) and prostaglandin E~2~ in ALS neurodegeneration. ## Methods Mutation in superoxide dismutase‐1 is a cause of the fatal paralytic disorder amyotrophic lateral sclerosis. Inhibition of cyclooxygenase‐2 (Cox‐2) in transgenic