𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Neck weakness is a potent prognostic factor in sporadic amyotrophic lateral sclerosis patients

✍ Scribed by Nakamura, R.; Atsuta, N.; Watanabe, H.; Hirakawa, A.; Watanabe, H.; Ito, M.; Senda, J.; Katsuno, M.; Tanaka, F.; Izumi, Y.; Morita, M.; Ogaki, K.; Taniguchi, A.; Aiba, I.; Mizoguchi, K.; Okamoto, K.; Hasegawa, K.; Aoki, M.; Kawata, A.; Abe, K.; Oda, M.; Konagaya, M.; Imai, T.; Nakagawa, M.; Tsuji, S.; Kaji, R.; Nakano, I.; Sobue, G.; Yuasa, T.; Kano, T.; Sasaki, H.; Kato, M.; Ishihara, T.; Nishizawa, M.; Ikeda, M.; Shibuya, K.; Kuwabara, S.; Hayashi, H.; Takahashi, Y.; Tomiyama, H.; Hattori, N.; Aizawa, H.; Kano, O.; Iwasaki, Y.; Nagasaka, T.; Takiyama, Y.; Sakai, M.; Shiga, K.; Yamashita, H.; Takahashi, R.; Fujita, T.; Yamashita, T.; Hiji, M.; Watanabe, Y.; Nakashima, K.; Hayashi, S.; Kira, J.-i.


Book ID
123613421
Publisher
BMJ Publishing Group
Year
2013
Tongue
English
Weight
829 KB
Volume
84
Category
Article
ISSN
0022-3050

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Corticomotor threshold is reduced in ear
✍ Kerry R. Mills; Kannan A. Nithi πŸ“‚ Article πŸ“… 1997 πŸ› John Wiley and Sons 🌐 English βš– 58 KB πŸ‘ 2 views

The pathogenesis of idiopathic amyotrophic lateral sclerosis (ALS) remains unknown, but accumulating evidence suggests a neuroexcitotoxic mechanism may have some credence. Glutamate-induced hyperexcitability of cortical or spinal motoneurons may be expected to manifest itself as a reduced threshold

Is prostaglandin E2 a pathogenic factor
✍ Gabriele Almer; Hitoshi Kikuchi; Peter Teismann; Serge Przedborski πŸ“‚ Article πŸ“… 2006 πŸ› John Wiley and Sons 🌐 English βš– 158 KB

## Abstract ## Objective To elucidate the role of cyclooxygenase‐1 (Cox1) and prostaglandin E~2~ in ALS neurodegeneration. ## Methods Mutation in superoxide dismutase‐1 is a cause of the fatal paralytic disorder amyotrophic lateral sclerosis. Inhibition of cyclooxygenase‐2 (Cox‐2) in transgenic