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P.07 Malnutrition is a significant prognosis factor in amyotrophic lateral sclerosis

✍ Scribed by J.C. Desport; P. Couratier; P.M. Preux; T.C. Truong; D. Sautereau

Book ID
117428956
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
291 KB
Volume
17
Category
Article
ISSN
0261-5614

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## Abstract ## Objective To elucidate the role of cyclooxygenase‐1 (Cox1) and prostaglandin E~2~ in ALS neurodegeneration. ## Methods Mutation in superoxide dismutase‐1 is a cause of the fatal paralytic disorder amyotrophic lateral sclerosis. Inhibition of cyclooxygenase‐2 (Cox‐2) in transgenic