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Pharmacokinetics of methotrexate after intravenous infusion of methotrexate-rabbit serum albumin conjugate to rabbits

✍ Scribed by Eun J. Yoon; Hong W. Chang; Myung G. Lee; Heejoo Lee; Man K. Park; Chong K. Kim

Book ID
113365616
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
565 KB
Volume
67
Category
Article
ISSN
0378-5173

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## Abstract The pharmacokinetics and tissue distribution of methotrexate (MTX) were investigated after intravenous (i.v.) injection of free MTX (treatment I), MTX‐loaded proliposomes (treatment II), and empty proliposomes mixed manually with free MTX (treatment III), 8 mg kg^βˆ’1^, to rats using an H