Automated solid-phase synthesis of branc
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Masad J. Damha; Steve Zabarylo
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Article
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1989
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Elsevier Science
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French
β 205 KB
A general procedure for the synthesis of branched RNA and DNA oligonucleotides has been developed. The synthetic strategy involves the 3'->5' synthesis of a DNA or RNA oligomer on a solid-phase, controlled-pore glass support with an automated DNA synthesizer. The branch point nucleoside is introduce