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Automated solid phase synthesis of cyclic oligonucleotides: a further improvement

✍ Scribed by Lorenzo De Napoli; Aldo Galeone; Luciano Mayol; Anna Messere; Daniela Montesarchio; Gennaro Piccialli


Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
474 KB
Volume
3
Category
Article
ISSN
0968-0896

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Automated solid-phase synthesis of branc
✍ Masad J. Damha; Steve Zabarylo πŸ“‚ Article πŸ“… 1989 πŸ› Elsevier Science 🌐 French βš– 205 KB

A general procedure for the synthesis of branched RNA and DNA oligonucleotides has been developed. The synthetic strategy involves the 3'->5' synthesis of a DNA or RNA oligomer on a solid-phase, controlled-pore glass support with an automated DNA synthesizer. The branch point nucleoside is introduce