Oligonucleotide synthesis on a crosslink
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Chander K. Narang; Kay Brunfeldt; Kjeld E. Norris
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Article
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1977
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Elsevier Science
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French
โ 275 KB
We wish to report the convenient stepwise synthesis of the pentanucleotide d-TpTpTpTpT, using commercially available crosslinked polyacrylmorpholide as an insoluble support. The conversion in each step ranged between 84 and 90% based