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A phosphoramidite reagent for automated solid phase synthesis of 5′-biotinylated oligonucleotides

✍ Scribed by Anthony J. Cocuzza

Publisher
Elsevier Science
Year
1989
Tongue
French
Weight
181 KB
Volume
30
Category
Article
ISSN
0040-4039

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✦ Synopsis

Biotin phosphoramidite 1 has been synthesized by a simple two-step procedure.

With this reagent 5'-biotinylated oligonucleotides are easily prepared usi.ng an automated DNA synthesizer.

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