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p21Waf1/cip1 expression

โœ Scribed by J.L. Rees


Book ID
108667132
Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
653 KB
Volume
136
Category
Article
ISSN
0007-0963

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RNase H 0 reverse transcriptase (GIBCO-BRL, Gaithersburg, MD). ase chain reaction; SSCP, single-strand conformation polymorphism; mRNA, messenger p21 WAF1/CIP1 messenger RNA (mRNA) was amplified with the follow-RNA; cdk, cyclin dependent kinase.

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BACKGROUND. p21(waf1/cip1) protein is a cyclin-dependent kinase inhibitor able to arrest the cell cycle at the G1 phase by inhibiting DNA replication. The expression of p21(waf1/cip1) and its prognostic value in prostate cancer are largely unexplored. METHODS. We used immunohistochemistry to analyze