𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Cell cycle arrest and DNA endoreduplication following p21Waf1/Cip1 expression

✍ Scribed by Bates, Stewart; Ryan, Kevin M; Phillips, Andrew C; Vousden, Karen H


Book ID
110061583
Publisher
Nature Publishing Group
Year
1998
Tongue
English
Weight
851 KB
Volume
17
Category
Article
ISSN
0950-9232

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Protease inhibitor–induced stabilization
✍ Qasim A. Khan; Anthony Dipple; Lucy M. Anderson 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 304 KB

## Abstract In previous studies, we have shown that human breast and lung carcinoma cells and mouse nontransformed type II lung cells fail to undergo cell‐cycle arrest in G~1~ phase in response to treatment with hydrocarbon carcinogens but rather accumulate in the S phase with damaged DNA. This sit

Smad pathway-specific transcriptional re
✍ Katerina Pardali; Marcin Kowanetz; Carl-Henrik Heldin; Aristidis Moustakas 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 724 KB

## Abstract Transforming growth factor‐β (TGF‐β) inhibits epithelial cell growth, in part via transcriptional induction of the cell cycle inhibitor p21^WAF1/Cip1^ (p21). We show that bone morphogenetic protein (BMP)‐7 induces higher p21 expression than TGF‐β1 in various epithelial cells. Despite th

TGF-β-induced cell-cycle arrest through
✍ Young D. Yoo; Ju-Youn Choi; Su-Jae Lee; Jun S. Kim; Byung-Re Min; Young I. Lee; 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 French ⚖ 211 KB 👁 1 views

## Transforming growth factor-␤1 (TGF-␤) inhibits cell-cycle progression of many types of cells by arresting them in G 1 /S phase through inhibition of the active cyclin-Cdk complexes that lead to inhibition of Rb phosphorylation. In gastriccancer cells, SNU16, TGF-␤ treatment induced enhanced exp