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p16INK4a inactivation is not required to immortalize human mammary epithelial cells

โœ Scribed by Herbert, Brittney-Shea; Wright, Woodring E; Shay, Jerry W


Book ID
110067046
Publisher
Nature Publishing Group
Year
2002
Tongue
English
Weight
286 KB
Volume
21
Category
Article
ISSN
0950-9232

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## Abstract Prostate cancer is a major cause of cancer death among male population. Therefore, development of appropriate model systems is critical for understanding the molecular basis of prostate cancer progression. In this study, introduction of human telomerase (hTERT) into normal human prostat