𝔖 Bobbio Scriptorium
✦   LIBER   ✦

P-Glycoprotein Deficiency in a Subpopulation of CF-1 Mice Enhances Avermectin-Induced Neurotoxicity

✍ Scribed by George R. Lankas; Mark E. Cartwright; Diane Umbenhauer


Book ID
112266359
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
963 KB
Volume
143
Category
Article
ISSN
0041-008X

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


The subpopulation of CF-1 mice deficient
✍ Todd R. Pippert; Diane R. Umbenhauer πŸ“‚ Article πŸ“… 2001 πŸ› John Wiley and Sons 🌐 English βš– 201 KB

## Abstract A subpopulation of the CF‐1 mouse strain is sensitive to neurotoxicity following exposure to avermectins, a family of structurally related antiparasitic agents. This unusual sensitivity is the result of a deficiency in the mdr1a P‐glycoprotein that normally contributes to a functional b