✦ LIBER ✦

Brain penetration of ivermectin and selamectin in mdr1a,b P-glycoprotein- and bcrp- deficient knockout mice

✍ Scribed by J. GEYER; O. GAVRILOVA; E. PETZINGER

Book ID: 108885343
Publisher: John Wiley and Sons
Year: 2009
Tongue: English
Weight: 248 KB
Volume: 32
Category: Article
ISSN: 0140-7783
DOI: 10.1111/j.1365-2885.2008.01007.x

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Development of an In Situ Mouse Brain Pe

Development of an In Situ Mouse Brain Perfusion Model and Its Application to mdr1a P-Glycoprotein-Deficient Mice

✍ Dagenais, Claude; Rousselle, Christophe; Pollack, Gary M.; Scherrmann, Jean-Mich 📂 Article 📅 2000 🏛 Nature Publishing Group 🌐 English ⚖ 417 KB

Brain penetration of methadone (R)- and

Brain penetration of methadone (R)- and (S)-enantiomers is greatly increased by P-glycoprotein deficiency in the blood–brain barrier of Abcb1a gene knockout mice

✍ Jun-Sheng Wang; Ying Ruan; RobinM. Taylor; JenniferL. Donovan; JohnS. Markowitz; 📂 Article 📅 2004 🏛 Springer 🌐 English ⚖ 184 KB

The role of P-glycoprotein in blood-brai

The role of P-glycoprotein in blood-brain barrier transport of morphine: transcortical microdialysis studies in mdr1a (−/−) and mdr1a (+/+) mice

✍ Rujia Xie; Margareta Hammarlund-Udenaes; Albertus G De Boer; Elizabeth C M De La 📂 Article 📅 1999 🏛 Nature Publishing Group 🌐 English ⚖ 156 KB

Increased accumulation of doxorubicin an

Increased accumulation of doxorubicin and doxorubicinol in cardiac tissue of mice lacking mdr1a P-glycoprotein

✍ Asperen, J van; Tellingen, O van; Tijssen, F; Schinkel, A H; Beijnen, J H 📂 Article 📅 1998 🏛 Nature Publishing Group 🌐 English ⚖ 55 KB

The subpopulation of CF-1 mice deficient

The subpopulation of CF-1 mice deficient in P-glycoprotein contains a murine retroviral insertion in the mdr1a gene

✍ Todd R. Pippert; Diane R. Umbenhauer 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 201 KB

## Abstract A subpopulation of the CF‐1 mouse strain is sensitive to neurotoxicity following exposure to avermectins, a family of structurally related antiparasitic agents. This unusual sensitivity is the result of a deficiency in the mdr1a P‐glycoprotein that normally contributes to a functional b

BBB Transport and P-glycoprotein Functio

BBB Transport and P-glycoprotein Functionality Using MDR1A (-/-) and Wild-Type Mice. Total Brain Versus Microdialysis Concentration Profiles of Rhodamine-123

✍ Elizabeth C. M. de Lange; Gertjan de Bock; Alfred H. Schinkel; Albertus G. de Bo 📂 Article 📅 1998 🏛 Springer US 🌐 English ⚖ 842 KB