The subpopulation of CF-1 mice deficient
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Todd R. Pippert; Diane R. Umbenhauer
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Article
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2001
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John Wiley and Sons
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English
⚖ 201 KB
## Abstract A subpopulation of the CF‐1 mouse strain is sensitive to neurotoxicity following exposure to avermectins, a family of structurally related antiparasitic agents. This unusual sensitivity is the result of a deficiency in the mdr1a P‐glycoprotein that normally contributes to a functional b